Rett syndrome is a debilitating neurological disease that mainly affects women and begins to develop after six months of life. Rett syndrome is most often misdiagnosed as autism, cerebral palsy, or nonspecific developmental delay. Rett syndrome is caused by a mutation on the X chromosome of a gene called MECP2. More than 200 different mutations were found in the MECP2 gene, and these mutations interfere with its ability to produce normal gene products. Rett Syndrome, which affects one in every 10,000 to 15,000 women born globally, causes problems with brain function, including cognitive, sensory, emotional, motor, and autonomic functions.Â