Charcot-Marie-Tooth disease

About Charcot-Marie-Tooth disease (CMT)

CMT is a disease affecting the peripheral nervous system that causes progressive muscle weakness and gradual loss of limb sensation from the lower limbs to the upper limbs. The disease is the most common hereditary neuromuscular disease and remains incurable. The first symptoms can appear in early childhood or after adulthood. The pathological mechanism of CMT involves more than 90 genes and contains quite a number of pathological processes. This complexity has led to its slow research progress and difficult treatment for a long time.